Ark Scientific - Laboratory Solutions

Automated Protein Digestion

Automated Protein Sample Preparation for HPLC and Mass Spectrometer Applications

SynQUAD-based Liquid Handling

ProPrep LC

Digilab ProPrep LC provides reliable high throughput protein digestion followed by sample preparation to LC/MS (Liquid Chromatography/Mass Spectrometry). It also offers a fully enclosed HEPA-filtered environment and the option of multiple reaction blocks. Take control of your protein samples.

Key features

  • Flow-through reaction blocks, 96 well format, temperature controlled
  • Reagent, chilling
  • Multi-enzyme use
  • Accurate liquid handling
  • In-gel or in-solution
  • Transfer to LC vials
  • Sample spitting
  • Customizable protocols and ability to run multiple protocols
  • Fully enclosed & HEPA filtered
SynQUAD-based Liquid Handling

ProPrep II

Digilab ProPrep II offers in-gel or in-solution protein digestion, with the ability to directly spot on to MALDI targets or to LC vials. The ProPrep II gives you piece of mind and provides your samples the best treatment.

Key features

  • Flow-through reaction blocks, 96 well format, temperature controlled
  • Reagent, chilling
  • Multi-enzyme use
  • Accurate liquid handling
  • In-gel or in-solution
  • Spotting to MALDI targets, accommodating all models
  • Transfer to LC, offline and online (optional)
  • Customizable protocols and ability to run multiple protocols
  • Fully enclosed & HEPA filtered
SynQUAD-based Liquid Handling

ProGest

Digilab ProGest Protein Digestion Station is an automated system for in-gel and in-solution digestion of proteins in order to prepare samples for LC/MS and/or MALDI/TOF (Matrix Assisted Laser Desorption/Ionization Time-of-Flight).

All washing steps, reduction (with DTT) and alkylation (with iodoacetamide) steps, enzyme activation and addition, and thermal incubation cycles are automatically performed and controlled using a touch screen interface. The unit can also be controlled using a desktop PC with the user-friendly Methods Editor software.

Key features

  • 96-well format in-solution or in-gel digestion
  • Multiple digestion runs per day
  • Flow-through reaction block with heating stage
  • Innovative concentric dual needle design
  • Aspiration-free sample processing
  • Fully enclosed
  • Unit can stand alone with touchpad control, or be PC-controlled
  • Methods include silver destaining, trypsin digestion, acidic and organic extraction